Publications from 2005 onwards

Applied Biotechnology

Peer reviewed articles

• Rathee G, Puertas-Segura A, Blair J, Rathee J and Tzanov T. Quantum dots@layered double hydroxides: Emerging nanocomposites for multifaceted applications. Progress in Materials Science, 2025. https://doi.org/10.1016/j.pmatsci.2024.101403
• Ferreres G, Pérez-Rafael S, Guaus E, Palacios O, Ivanov I, Torrent-Burgués J and Tzanov T. Antimicrobial and antifouling hyaluronic acid-cobalt nanogel coatings built sonochemically on contact lenses. Ultrasonics Sonochemistry, 2024. https://doi.org/10.1016/j.ultsonch.2024.107131  
• Havryliuk O, Rathee G, Blair J, Hovorukha V, Tashyrev O, Morató J, Pérez LM and Tzanov T. Unveiling the Potential of CuO and Cu2O Nanoparticles against Novel Copper-Resistant Pseudomonas Strains: An In-Depth Comparison. Nanomaterials, 2024. https://doi.org/10.3390/nano14201644
• Pérez LM, Havryliuk O, Infante N, Muniesa M, Morató J, Mariychuck R and Tzanov T. Biofilm Prevention and Removal in Non-Target Pseudomonas Strain by Siphovirus-like Coliphage. Biomedicines, 2024. https://doi.org/10.3390/biomedicines12102291
• Ivanova K, Ramon E, Wnorowska U, Todorova K, Ivanova A, Bastos-Arrieta J, Puertas-Segura A, Deptula P, Damyanova T, Paunov-krasteva T, Bucki R, Ivanov I and Tzanov T. Integrated Biofilm Dispersion and Virulence Responsiveness for Targeted Treatment of Pseudomonas aeruginosa Infection in Lungs. Advanced Functional Materials, 2024.  https://doi.org/10.1002/adfm.202402868
• Rafiei S, Ghanbari‐A M, Zeinali R, Heidari‐K S, Rahimi A, Royanian F, Zaeifi D, Taheri K, Pourtaghi K, Khaleghi M, Biazar E. Silk fibroin/vitreous humor hydrogel scaffold modified by a carbodiimide crosslinker for wound healing. Biopolymers 2024, https://doi.org/10.1002/bip.23612
• Biazar E, Aavani F, Zeinali R, Kheilnezhad B, Taheri K, Yahyaei Z. Delivery Systems for Plasma-reactive Species and their Applications in the Field of Biomedicine. Current Drug Delivery 2024, https://doi.org/10.2174/0115672018268207231124014915
• Puertas-Segura A, Ivanova K, Ivanova A, Ivanov I, Todorova K, Dimitrov P, Ciardelli G and Tzanov T. Mussel-Inspired Sonochemical Nanocomposite Coating on Cartheters for Prevention of Urinary Infections. ACS Applied Materials & Interfaces. 2024. https://doi.org/10.1021/acsami.4c05713 .
• Carvalho E, Fernandes M, Ivanova K, Rodríguez-Lejarraga P, Tzanov T, Ribeiro C and Lanceros-Mendez S. Multifunctional piezoelectric surfaces enhanced with layer-by-layer coating for improved osseointegration and antibacterial performance. Colloids and surfaces B: Biointerfaces, 2024. https://doi.org/10.1016/j.colsurfb.2024.114123
• Mingot J, Lanzalaco S, Ferreres G, Tzanov T, Alemán C and Armelin E. Theranostic nano-enabled polyurethane eso-sponges coupled to surface enhanced Raman scattering for detection and control of bacteria killing. Chemical Engineering Journal, 2024. https://doi.org/10.1016/j.cej.2024.154617
• Bragato C, Persico A, Ferreres G, Tzanov T and Mantecca P. Exploring the Effects of Lignin Nanoparticles in Different Zebrafish Inflammatory Models. International Journal of Nanomedicine, 2024. https://doi.org/10.2147/IJN.S469813
• Puertas-Segura A, Morena A G, Pérez-Rafael S, Ivanova K, Ivanov I, Todorova K, Dimitrov P, Ciardelli G and Tzanov T. Enzymatically Built Nanoenabled Antimicrobial Coating on Urinary Catheters. ACS Applied Materials & Interfaces, 2024. https://doi.org/10.1021/acsami.4c08599
• Ferreres G, Pérez-Rafael S, Palacios Ó, Todorova K, Hinojosa-Caballero D, Torrent-Burgués J and Tzanov T. Cobalt-phenolic nanoparticles-driven self-assembly of hyaluronic acid hydrogels providing a multifactorial approach for chronic wound management. Chemical Engineering Journal, 2024. https://doi.org/10.1016/j.cej.2024.153064.
• Resina L, Esteves T, Pérez-Rafael S, Hernández García J I, Castelo Ferreira F, Tzanov T, Bonardd S, Díaz Díaz D, Pérez-Madrigal, M M, Alemán C. Dual electro-/pH-responsive nanoparticle/hydrogel system for controlled delivery of anticancer peptide, Biomater Adv, 2024. https://doi.org/10.1016/j.bioadv.2024.213925
• Perelshtein I, Shoshani S, Jacobi G, Natan M, Dudchenko N, Perkas N, Tkachev M, Bengalli R, Fiandra L, Mantecca P, Ivanova K, Tzanov T, Banin E, Gedanken A. Protecting the Antibacterial Coating of Urinal Catheters for improving Safety. ACS Appl. Bio Mater, 2024. https://doi.org/10.1021/acsabm.3c00988
• Ferreres G, Pérez-Rafael S, Morena A G, Tzanov T, Gryshchuk L. Influence of Enzymatically Hydrophobized Hemp Protein on Morphology and Mechanical Properties of Bio-Based Polyurethane and Epoxy Foams. Polymers, 2023. https://doi.org/10.3390/polym15173608
  
• Pérez-Rafael S, Ferreres G, Kessler W R, Kessler W, Blair J, Rathee G, Morena A G,  Tzanov T. Continuous sonochemical nanotransformation of lignin - Process design and control. Ultrasonics Sonochemistry, 2023. https://doi.org/10.1016/j.ultsonch.2023.106499
• Gutiérrez-Capitán M, Sanchís A, O. Carvalho E, Baldi A, Vilaplana Ll, F. Cardoso V, Calleja Á, Wei M, de la Rica R, Hoyo J, Bassegoda A, Tzanov T, Marco M, Lanceros-Méndez S, Fernández-Sánchez C. Engineering a Point-of-Care Paper-Microfluidic Electrochemical Device Applied to the Multiplexed Quantitative Detection of Biomarkers in Sputum. ACS Sensors, 2023. https://doi.org/10.1021/acssensors.3c00523
• Crivello G, Orlandini G, Gala A, Torchio A, Mattu C, Boffito M, Tzanov T, Giardelli G. Lignin–Cobalt Nano-Enabled Poly(pseudo)rotaxane Supramolecular Hydrogel for Treating Chronic Wounds. Pharmaceutics, 2023. https://doi.org/10.3390/pharmaceutics15061717
• Ferreres G, Ivanova K, Torrent-Burgués J, Tzanov T. Multimodal silver-chitosan-acylase nanoparticles inhibit bacterial growth and biofilm formation by Gram-negative Pseudomonas aeruginosa bacterium. Journal of Colloid and Interface Science, 2023. https://doi.org/10.1016/j.jcis.2023.04.184
• Ferreres G, Ivanova K, Ivanov I, Tzanov T.  Nanomaterials and Coatings for Managing Antibiotic-Resistant Biofilms. Antibiotics 2023,  https://doi.org/10.3390/antibiotics12020310
• Ivanova K, Ramon E, Ivanova A, Sanchez-Gomez S, Tzanov T. Bio-Based Nano-Enabled Cosmetic Formulations for the Treatment of Cutibacterium Acnes-Associated Skin Infections. Antioxidants 2023, https://doi.org/10.3390/antiox12020432
• Recupido F, Lama G C, Ammendola M, De Luca Bossa F, Minigher A, Campaner P, Morena A G, Tzanov T, Ornelas M, Barros A, Gomes F, Bouça V, Malgueiro R, Sanchez M, Martinez M, Sorrentino L, Boggioni L, Perucca M, Anegalla S, Marzella R, Moimare P, Verdolotti L. Rigid enabled composite bio-based polyurethane foams: from synthesis to LCA analysis. Polymer, 2023, https://doi.org/10.1016/j.polymer.2023.125674 
  
• Morena A G, Pérez-Rafael S, Tzanov T. Lignin-Based Nanoparticles as Both Structural and Active Elements in Self-Assembling and Self-Healing Multifunctional Hydrogels for Chronic Wound Management. Pharmaceutics 2022,  https://doi.org/10.3390/pharmaceutics14122658
• Fernandes M, Carvalho E, Correia D, Esperança J, Padrao J, Ivanova K, Hoyo J, Tanov T, Lanceros-Mendez S. Ionic Liquids as Biocompatible Antibacterial Agents: A Case Study on Structure-Related Bioactivity on Escherichia coli. ACS Applied Materials & Interfaces, 2022. https://pubs.acs.org/doi/10.1021/acsabm.2c00615
• Morena A. G, Tzanov T. Antibacterial lignin-based nanoparticles and their use in composite materials. Nanoscale Advances, 2022. https://pubs.rsc.org/hi/content/articlelanding/2022/na/d2na00423b
• Bermeo L, Ivanova K, Pérez, L M, Forés E, Pérez-Rafael S, Casas-Zapata J C C, Morató J, Tzanov T. Sono-Enzymatically Embedded Antibacterial Silver-Lignin Nanoparticles on Cork Filter Material for Water Disinfection. International Journal of Molecular Sciences. 2022, 23, 11679. https://doi.org/10.3390/ijms231911679.
• Morena A G, Bassegoda A, Natan M, Jacobi G, Banin E, Tzanov T. Antibacterial Properties and Mechanisms of Action of Sonoenzymatically Synthesized Lignin-Based Nanoparticles. ACS Applied Materials & Interfaces. 2022, https://doi.org/10.1021/acsami.2c05443.
• Hoyo J, Bassegoda A, Ferrers G, Hinojosa D, Gutiérrez M, Baldi A, Fernández C, Tzanov T. Rapid Colorimetric Detection of Wound Infection with a Fluidic Paper Device. International Journal of Molecular Sciences. 2022, https://doi.org/10.3390/ijms23169129.
• Ivanova K, Ivanova A, Hoyo J, Pérez-Rafael S, Tzanov T. Nano-Formulation Endows Quorum Quenching Enzyme-Antibiotic Hybrids with Improved Antibacterial and Antibiofilm Activities against Pseudomonas aeruginosa. International Journal of Molecular Sciences. 2022, https://doi.org/10.3390/ijms23147632.
• Ivanova A, Ivanova K, Fiandra L, Mantecca P, Catelani T, Natan M, Banin E, Jacobi G, and Tzanov T. Antibacterial, Antibiofilm, and Antiviral Farnesol-Containing Nanoparticles Prevent Staphylococcus aureus from Drug Resistance Development. International Journal of Molecular Sciences. 2022, https://doi.org/10.3390/ijms23147527.
• Ruffo M., Ilaria I., Dattilo M., Patitucci F., Malivindi R., Pezzi V., Tzanov T., Puoci F., Synthesis and evaluation of wound healing properties of hydro-diab hydrogel loaded with green-synthetized AGNPS: in vitro and in ex vivo studies. Drug Deliv. and Transl. Res.(2022). https://doi.org/10.1007/s13346-022-01121-w
  
• Iglesias-Mayor, A., Amor-Gutiérrez, O., Toyos-Rodríguez, C., Bassegoda, A.,Tzanov, T., Escosura-Muñiz, A.d.l., Electrical monitoring of infection biomarkers in chronic wounds using nanochannels, Biosensors and Bioelectronics (2022), doi: https://doi.org/10.1016/j.bios.2022.114243.
  
• Hoyo, J., Bassegoda, A., Tzanov, T. Electrochemical quantification of biomarker myeloperoxidase, Zeitschrift für Naturforschung. Section C, a Journal of Biosciences, 2022, https://doi.org/10.1515/znc-2021-0274
  
• Ferreres G, Pérez-Rafael S, Torrent-Burgués J, and Tzanov T. Hyaluronic Acid Derivative Molecular Weight-Dependent Synthesis and Antimicrobial Effect of Hybrid Silver Nanoparticles. International Journal of Molecular Sciences, 2021, https://doi.org/10.3390/ijms222413428
• Ivanova A, Ivanova K, and Tzanov T. Simultaneous ultrasound-assisted hybrid polyzwitterion/antimicrobial peptide nanoparticles synthesis and deposition on silicone urinary catheters for prevention of biofilm-associated infections. Nanomaterials, 2021, http://doi.org/10.3390/nano11113143
• Ivanova A, Ivanova K, Perelshtein I, Gedanken A, Todorova K, Milcheva R, Dimitrov P, Popova T, Tzanko T. Sonochemically Engineered Nano-enabled Zinc Oxide/Amylase Coatings Prevent the Occurrence of Catheter-Associated Urinary Tract Infections. Materials Science & Engineering C 2021.   doi: 10.1016/j.msec.2021.112518
• Slavin Y N, Ivanova K, Tang W, Tzanov T, Li S, Bach H. Targeting Intracellular Mycobacteria Using Nanosized Niosomes Loaded with Antibacterial Agents. Nanomaterials 2021, https://doi.org/10.3390/nano11081984.
• Pérez-Rafael S, Ivanova K, Stefanov I, Puiggalí J, del Valle L J, Todorova K, Dimitrov P,  Hinojosa-Caballero D, Tzanov, T. Nanoparticle-driven Self-assembling Injectable Hydrogels Provide a Multi-factorial Approach for Chronic Wound Treatment. Acta Biomaterialia 2021, https://doi.org/10.1016/j.actbio.2021.07.020.
• Torrent-Burgués J, Hoyo J, Tzanko T. Lipid Artificial Tears at a Mimetic Ocular Interface.  Chem. Phys. Lipids 2021, https://doi.org/10.1016/j.chemphyslip.2021.105087.
• Slavin Y N, Ivanova K, Hoyo J, Perelshtein I, Owen G, Haegert A, Lin Y, LeBihan S, Gedanken A, Häfeli U O, Tzanov T, Bach H. Novel Lignin-Capped Silver Nanoparticles against MultidrugResistant Bacteria, ACS Applied Materials & Interfaces 2021, https://doi.org/10.1021/acsami.0c16921.
• Morena A G, Bassegoda A, Hoyo J, Tzanov T. Hybrid Tellurium–Lignin Nanoparticles with Enhanced Antibacterial Properties, ACS Applied Materials & Interfaces 2021, https://doi.org/10.1021/acsami.0c22301.
• Ferrer-Vilanova A, Alonso Y, Dietvorst J, Pérez-Montero M, Rodriguez R, Ivanova K, Tzanov T, Vigues N, Mas J, Guirado G, Muñoz-Berbel X. Sonochemical Coating of Prussian Blue for the Production of Smart Bacterial Sensing Hospital Textiles, Ultrasonics Sonochemistry 2020, https://doi.org/10.1016/j.ultsonch.2020.105317.
• Braunschmid V, Fuerst S, Perz V, Zitzenbacher S, Hoyo J, Fernández-Sánchez C, Tzanov T, Steinkellner G, Gruber K, Nyanhongo G S, Ribitsch D, Guebitz G M. A Fungal Ascorbate Oxidase with Unexpected Laccase Activity. International Journal of Molecular Sciences 2020, https://doi.org/10.3390/ijms21165754.
• Ivanova K, Ivanova A, Ramon E, Hoyo J, Sanchez-Gomez S, Tzanov T. Antibody-Enabled Antimicrobial Nanocapsules for Selective Elimination of Staphylococcus aureus. ACS Applied Materials & Interfaces 2020, http://dx.doi.org/10.1021/acsami.0c09364.
• Hoyo J, Ivanova K, Torrent-Burgués J, Tzanov T. Interaction of Silver-Lignin Nanoparticles With Mammalian Mimetic Membranes. Frontiers in Bioengineering and Biotechnology 2020, https://doi.org/10.3389/fbioe.2020.00439.
• Lapo B, Bou J, Hoyo J, Carrillo M, Peña K, Tzanov T, Sastre AM. A potential lignocellulosic biomass based on banana waste for critical rare earths recovery from aqueous solutions. Environmental Pollution 2020, https://doi.org/10.1016/j.envpol.2020.114409.
• Ivanova A, Ivanova K, Tied A, Heinze T, and Tzanov T. Layer-by-Layer Coating of Aminocellulose and Quorum Quenching Acylase on Silver Nanoparticles Synergistically Eradicate Bacteria and Their Biofilms. Advanced Functional Materials 2020, https://doi.org/10.1002/adfm.202001284.
• Ruseva K, Ivanova K, Todorova K, Vladov I, Nanev V, Tzanov T, Hinojosa-Caballero D, Argirova M, Vassileva E. Antibiofilm poly(carboxybetaine methacrylate) hydrogels for chronic wounds dressings. European Polymer Journal 2020, doi: https://doi.org/10.1016/j.eurpolymj.2020.109673.
• Hoyo J, Torrent-Burgués J, Tzanov T. Lipid-lipid interactions of Escherichia coli mimetic inner membrane at human physiological temperature. Gen. Physiol. Biophys. 2020, 39, 195-202, doi: https://doi.org/10.4149/gpb_2019063.
• Morena A G, Stefanov I, Ivanova K, Pérez-Rafael S, Sánchez-Soto M, Tzanov T. Antibacterial Polyurethane Foams with Incorporated Lignin-Capped Silver Nanoparticles for Chronic Wound Treatment. Industrial and Engineering Chemistry Research 2020, doi: https://doi.org/10.1021/acs.iecr.9b06362.
• Ruseva K, Ivanova K, Todorova K, Gabrashanska M, Hinojosa-Caballero D, Tzanov T, Vassileva E. Poly(sulfobetaine methacrylate)/poly(ethylene glycole) hydrogels for chronic wounds management, European Polymer Journal 2019, doi: https://doi.org/10.1016/j.eurpolymj.2019.05.022.
• de la Escosura-Muñiz A, Ivanova K, Tzanov T. Electrical evaluation of bacterial virulence factors using nanopores. ACS Applied Materials & Interfaces 2019, doi: https://doi.org/10.1021/acsami.9b02382. 
• Hoyo J, Ivanova K, Guaus E, Tzanov T. Multifunctional ZnO NPs-chitosan-gallic acid hybrid nanocoating to overcome contact lenses associated conditions and discomfort. Journal of Colloids and Interface Science 2019, https://doi.org/10.1016/j.jcis.2019.02.043.
• Ferrer-Vilanova A, Ivanova K, Díaz-González M, Alonso Y, Guirado G, Tzanov T, Muñoz-Berbel X. Smart sensing fabrics for live bacteria detection. Proceedings 2018, doi: https://doi.org/10.3390/proceedings2130916.
• Hoyo J, Torrent-Burgués J, Tzanov T. Physical states and thermodynamic properties of model Gram-negative bacterial inner membranes. Chemistry and Physics of Lipids, 2018, doi: https://doi.org/10.1016/j.chemphyslip.2018.12.003
• Ferreres G, Bassegoda A, Hoyo J, Torrent-Burgués J, Tzanov T. Metal-enzyme nanoaggregates eradicate both Gram positive and negative bacteria and their biofilms. ACS Applied Materials & Interfaces 2018,  doi: https://doi.org/10.1021/acsami.8b14949.
• Stefanov I, Hinojosa-Caballero D, Maspoch S, Hoyo J, Tzanov T. Enzymatic Synthesis of a Thiolated Chitosan-Based Wound Dressing Crosslinked with Chicoric Acid. Journal of Materials Chemistry B 2018, doi: https://doi.org/10.1039/C8TB02483A.
• Bassegoda A, Ferreres G, Pérez-Rafael S, Hinojosa-Caballero D, Torrent-Burgués J, Tzanov T. New myeloperoxidase detection system based on enzyme-catalysed oxidative synthesis of a dye for paper-based diagnostic devices, Talanta 2018, doi: https://doi.org/10.1016/j.talanta.2018.10.065.
• Francesko A, Ivanova K, Hoyo J, Pérez-Rafael S, Petkova P, Fernandes M M, Heinze T, Mendoza E, Tzanov T. Bottom-up layer-by-layer assembling of antibacterial freestanding nanobiocomposite films, Biomacromolecules 2018, doi: https://doi.org/10.1021/acs.biomac.8b00626.
• Salat M, Petkova P, Hoyo J, Perelshtein I, Gedanken A, Tzanov T. Durable antimicrobial cotton textiles coated sonochemically with ZnO nanoparticles embedded in an in-situ enzymatically generated bioadhesive. Carbohydrate Polymers 2018, doi: https://doi.org/10.1016/j.carbpol.2018.02.033.
• Bassegoda A, Ivanova K, Ramon E, Tzanov T. Strategies to prevent the occurrence of resistance against antibiotics by using advanced materials. Applied Microbiology and Biotechnology 2018, doi: https://doi.org/10.1007/s00253-018-8776-0, http://rdcu.be/F6jE.
• Ivanova A, Ivanova K, Hoyo J, Heinze T, Sanchez-Gomez S, Tzanov T. Layer-by-layer decorated nanoparticles with tunable antibacterial and antibiofilm properties against both gram-positive and gram-negative bacteria. ACS Applied Materials & Interfaces 2018, doi: https://doi.org/10.1021/acsami.7b16508.
• Francesko A, Petkova P, Tzanov T. Hydrogel dressings for advanced wound management. Current Medicinal Chemistry 2017, doi: https://doi.org/10.2174/0929867324666170920161246.
• Ivanova K, Ramon E, Hoyo J, Tzanov T. Innovative approaches for controlling clinically relevant biofilms: current trends and future prospects. Current Topics in Medicinal Chemistry 2017, doi: 10.2174/1568026617666170105143315.
• Stefanov I, Pérez-Rafael S, Hoyo J, Cailloux J, Santana Pérez O O, Hinojosa-Caballero D, Tzanov T. Multifunctional enzymatically-generated hydrogels for chronic wound application. Biomacromolecules 2017, doi: 10.1021/acs.biomac.7b00111.
• Francesko A, Fossas Marta C, Petkova P, Fernandes M M, Mendoza E, Tzanov T. Sonochemical synthesis and stabilization of concentrated antimicrobial silver-chitosan nanoparticle dispersions. Journal of Applied Polymer Science 2017, doi: 10.1002/APP.45136.
• Fernandes M M, Ivanova K, Hoyo J, Pérez-Rafael S, Francesko A, Tzanov T. Nanotransformation of vancomycin overcomes the intrinsic resistance of Gram-negative bacteria. ACS Applied Materials & Interfaces 2017, doi: 10.1021/acsami.7b00217.
• Garcia Peña L V, Petkova P, Margalef-Marti R, Vives M, Aguilar L, Gallegos A, Francesko A, Perelshtein I, Gedanken A, Ernest M, Casas-Zapata J C,Morató J, Tzanov T. Hybrid chitosan−silver nanoparticles enzymatically embedded on cork filter material for water disinfection. Industrial & Engineering Chemistry Research 2017, doi: 10.1021/acs.iecr.6b04721.
• Fernandes M M, Ivanova K, Francesko A, Mendoza E, Tzanov T. Immobilization of antimicrobial core-shell nanospheres onto silicone for prevention of Escherichia coli biofilm formation. Process Biochemistry 2016, doi: 10.1016/j.procbio.2016.09.011.
• Fernandes M M, Ivanova K, Francesko A, Rivera D, Torrent-Burgués J,   Gedanken A,  Mendoza E, Tzanov T.  Escherichia coli and Pseudomonas aeruginosa eradication by nano-penicillin G Nanomedicine: Nanotechnology, Biology and Medicine 2016, 12, 2061-2069, doi:10.1016/j.nano.2016.05.018.
• Francesko A, Fernandes M M, Ivanova K, Amorim S, Reis R L, Pashkuleva I, Mendoza E, Pfeifer A, Heinze T, Tzanov T. Bacteria-responsive multilayer coatings comprising polycationic nanospheres for bacteria biofilm prevention on urinary catheters. Acta Biomaterialia 2016, doi: http://dx.doi.org/10.1016/j.actbio.2016.01.020
• Perelshtein I, Lipovsky A, Perkas N, Tzanov T, Gedanken A. Sonochemical co-deposition of antibacterial nanoparticles and dyes on textiles. Beilstein Journal of Nanotechnology 2016, 7, 1-8, doi: 10.3762/bjnano.7.1.
• Petkova P, Francesko A, Perelshtein I, Gedanken A, Tzanov T. Simultaneous sonochemical-enzymatic coating of medical textiles with antibacterial ZnO nanoparticles. Ultrasonics Sonochemistry 2016, 29, 244 - 250, doi:10.1016/j.ultsonch.2015.09.021.
• Ivanova K, Fernandes M M, Francesko A,Guezguez J, Burnet M, Mendonza E, Tzanov T. Quorum quenching and matrix degrading enzymes in multilayer coatings synergistically prevent bacterial biofilm formation on urinary catheters. ACS Applied Materials & Interfaces 2015, doi: 10.1021/acsami.5b09489, http://pubs.acs.org/articlesonrequest/AOR-C2ftuuKenNNQY6f4kPSS
• Thallinger B, Brandauer M, Burger P, Sygmund C, Ludwig R, Ivanova K, Kun J, Scaini D, Burnet M, Tzanov T, Nyanhongo G, Guebitz G. Cellobiose dehydrogenase functionalized urinary catheter as novel antibiofilm system. Journal of Biomedical Materials Research Part B: Applied Biomaterials 2015, doi: 10.1002/jbm.b.33491
• Fernandes MM, Rivera D, Francesko A, Šližytė R, Mozuraitytė R, Rommi K, Lantto R, Tzanov T. Bio/Sonochemical conversion of fish backbones into bioactive nanospheres. Process Biochemistry 2015, doi:10.1016/j.procbio.2015.08.001.
• Cusola O, Valls C, Vidal T, Tzanov T, Roncero MB. Electrochemical insights on the hydrophobicity of cellulose substrates imparted by enzymatically-oxidized gallates with increasing alkyl chain length. ACS Applied Materials & Interfaces 2015, doi: 10.1021/acsami.5b01904.
• Zille A, Fernandes MM, Francesko A, Tzanov T, Fernandes M, Oliveira FR, Almeida L, Amorim T, Carneiro N, Esteves MF, Souto AP. Size and aging effects on antimicrobial efficiency of silver nanoparticles coated on polyamide fabrics activated by atmospheric DBD plasma. ACS Applied Materials & Interfaces 2015, doi: 10.1021/acsami.5b04340.
• Francesko A, Blandón L, Vázquez M, Petkova P, Morato J, Pfeifer A, Heinze T, Mendoza E, Tzanov T. Enzymatic functionalization of cork surface with antimicrobial hybrid biopolymer/silver nanoparticles. ACS Applied Materials & Interfaces 2015, doi: 10.1021/acsami.5b01670.
• Rivera D, Rommi K, Fernandes MM, Lantto R, Tzanov T. Biocompounds from Rapeseed oil industry co-stream as active ingredients for skin care applications. International Journal of Cosmetic Science 2015, doi:10.1111/ics.12222.
• Erencia M, Cano F, Tornero JA, Fernandes MM, Tzanov T, Macanás J, Carrillo F. Electrospinning of gelatin fibers using solutions with low acetic acid concentration: Effect of solvent composition on both diameter of electrospun fibers and cytotoxicity. Journal of applied polymer science 2015, 132, 42115 (1-11).
• Petkova P, Francesko A, Tzanov T. Enzyme-assisted formation of hybrid biopolymer hydrogels incorporating active phenolic nanospheres. Engineering in Life Sciences 2015, doi: 10.1002/elsc.201400143.
• Perelshtein I, Lipovsky A, Perkas N, Tzanov T, Arquirova M, Lesseva M, Gedanken A. Making the hospital a safer place by sonochemical coating of all its textiles with antibacterial nanoparticles. Ultrasonics Sonochemistry 2015, doi: 10.1016/j.ultsonch.2014.12.012.
• Ivanova K, Fernandes MM, Mendonza E, Tzanov T. Enzyme multilayer coatings inhibit Pseudomonas aeruginosa biofilm formation on urinary catheters. Applied Microbiology and Biotechnology 2015, doi: 10.1007/s00253-015-6378-7.
• Francesko A, Fernandes MM, Perelshtein I, Benisvy-Aharonovich L, Gedanken A, Tzanov T. One-step sonochemical preparation of redox-responsive nanocapsules for glutathione mediated RNA release. Journal of Materials Chemistry B 2014, 2, 6020-6029.
• Diaz Blanco C, Ortner A, Dimitrov R, Navarro A, Mendoza E, Tzanov T. Building an antifouling zwitterionic coating on urinary catheters using and enzymatically-triggered bottom-up approach. Applied Materials and Interfaces 2014, 6(14), 11385-11393.
• Fernandes MM, Francesko A, Torrent-Burgués J, Carrión-Fité FJ, Heinze T, Tzanov T. Sonochemically processed cationic nanocapsules - efficient antimicrobials with membrane disturbing capacity. Biomacromolecules 2014, 15(4), 1365-1374.
• Molina R, Jovancic P, Vilchez S, Tzanov T, Solans S. In situ chitosan gelation initiated by atmospheric plasma treatment, Carbohydrate Polymers 2014, 103, 472-479.
• Aracri E, Diaz Blanco C, Tzanov T. An enzymatic approach to develop a lignin-based adhesive for wool floor coverings, Green Chemistry 2014,16(5), 2597-2603.
• Petkova P, Francesko A, Fernandes MM, Mendoza E, Perelshtein I, Gedanken A, Tzanov T. Sonochemical coating of textiles with hybrid ZnO/chitosan antimicrobial nanoparticles. ACS Applied Materials & Interfaces 2014, 6(2), 1164-1172.
• Perelshtein I, Ruderman E, Francesko A, Fernandes MM, Tzanov T, Gedanken A. Tannic acid NPs – Synthesis and immobilization onto a solid surface in a one-step process and their antibacterial and anti-inflammatory properties. Ultrasonics Sonochemistry 2014, 21(6),1916-1920.
• Fernandes M M, Francesko A, Torrent-Burgués J, Tzanov T. Effect of thiol-functionalisation on chitosan antibacterial activity: interaction with a bacterial membrane model. Reactive and Functional Polymers, 2013, 73 (10),1384–1390.
• Aracri E, Tzanov T, Vidal T. Use of Cyclic Voltammetry as an Effective Tool for Selecting Efficient Enhancers for Oxidative Bioprocesses: Importance of pH. Industrial & Engineering Chemistry Research  2013, 52(4),1455-1463.
• Perelshtein I, Ruderman E, Perkas N, Tzanov T, Beddow J, Joyce E, Mason T J, Blanes M, Molla K, Patlolla A, Frenkel A I, Gedanken A. Chitosan and chitosan-ZnO-based complex nanoparticles: formation, characterization, and antibacterial activity. Journal of Materials Chemistry B 1, 2013, 1968-1976.
• Rocasalbas G, Francesko A, Touriño S, Fernández-Francos X, Guebitz G M, Tzanov T. Laccase-assisted formation of bioactive chitosan/gelatin hydrogel stabilized with plant polyphenols. Carbohydrate Polymers 2013, 92, (2), 989-996.
• Rocasalbas G, Tourino S, Torres J L, Tzanov T. A new approach to produce plant antioxidant-loaded chitosan for modulating proteolytic environment and bacterial growth. Journal of Materials Chemistry B 1 2013, 1241-1248.
• Perelshtein I, Ruderman Y, Perkas N, Traeger K, Tzanov T, Beddow J, Joyce E, Mason T J, Blanes M, Molla K, Gedanken A. Enzymatic pre-treatment as a means of enhancing the antibacterial activity and stability of ZnO nanoparticles sonochemically coated on cotton fabrics. Journal of Materials Chemistry 2012, 22(21), 10736-10742.
• Díaz Blanco C, Trifonov A, Georgiev G, Tzanov T. Light harvesting amphiphiles boost the performance of lipase-based washing formulations. Enzyme and Microbial Technology 2012, 51, 156-162.
• Díaz Blanco C, Trifonov A, Georgiev G, Tzanov T. Hematoporphyrin-based amphiphiles boost the washing performance of protease-containing formulations in a biomimetic approach. Journal of Molecular Catalysis B: Enzymatic  (2012), 78, 45– 50.
• Francesko A, Soares da Costa D, Reis R L, Pashkuleva I, Tzanov T. Functional biopolymer-based matrices for modulation of chronic wound enzyme activities. Acta Biomaterialia 2012, 9, 5216-5225.
• Díaz-González M, Rocasalbas G, Francesko A, Touriño S, Torres JL, Tzanov T. Inhibition of deleterious chronic wound enzymes with plant polyphenols. Biocatalysis and Biotransformation 2012, 30 102-110.
• Francesko A, Soares da Costa D, Lisboa P, Reis R L, Pashkuleva I, Tzanov T.  GAGs-thiolated chitosan assemblies for chronic wounds treatment: control of enzyme activity and cell attachment. Journal of Materials Chemistry 2012, 22, 19438-19446.
• Díaz-González M, Vidal T, Tzanov T. Phenolic compounds as enhancers in enzymatic and electrochemical oxidation of veratryl alcohol and lignins. Applied Microbiology and Biotechnology 2011, 89(6), 1693-1700.
• Francesko A, Rocasalbas G, Touriño S, Mattu C, Gentile P, Chiono V, Ciardelli G, Tzanov T. Cross-linked collagen sponges loaded with plant polyphenols with inhibitory activity towards chronic wound enzymes. Biotechnology Journal 2011, 6(10), 1208-1218.
• Hasmann A, Gewessler U, Hulla E, Schneider K P, Binder B, Francesko A, Tzanov T, Schintler M, Van der Palen J, Guebitz G M, Wehrschuetz-Sigl E. Sensor materials for the detection of human neutrophil elastase and cathepsin G activity in wound fluid. Experimental Dermatology 2011, 20(6), 508-513.
• Fernandes M M, Gomes AC, Vasconcelos A, Munteanu F D, Tzanov T, Gonçalves M S, End N, Schoening K U, Guebitz G M, Cavaco-Paulo A. Protein disulphide isomerase-assisted functionalization of keratin-based matrices. Applied Microbiology and Biotechnology. Applied Microbiology and Biotechnology 2011, 90,  1311-1321.
• Hossain G, Díaz M, Dagá J.Mª, Tzanov T. Effects of alkyl chain lengths of gallates upon enzymatic wool functionalisation. Journal of molecular catalysis B. Enzymatic 2010, 67,  231-235.
• Skirtenko N, Tzanov T, Gedanken A, Rahimipour S. One-Step Preparation of Multifunctional Chitosan Microspheres by a Simple Sonochemical Method. Chemistry a European Journal 2010, 16 (2),  562-567.
• Hossain G, Díaz M, Riva A, Tzanov T. Enzyme-mediated coupling of a bi-functional phenolic compound onto wool to enhance its physical, mechanical and functional properties. Enzyme and Microbial Technology 2010, 46, 326-330.
• González M D, Vidal T, Tzanov T. Electrochemical study of phenolic compounds as enhancers in laccase-catalyzed oxidative reactions, Electroanalysis 2009, 21,  2249-2257.
• Božič M, Díaz M, Tzanov T, Guebitz G, Kokol V. Voltametric monitoring of enzyme-mediated indigo reduction in the presence of various fibre materials. Enzyme Microb. Technol. 2009, 317-32.
• Díaz C, Díaz M, González Dagá J M, Tzanov T. Dyeing properties, synthesis, isolation and characterization of an in situ generated phenolic pigment, covalently bound to cotton. Enzyme Microb. Technol.  2009, 44, 380-385.
• Hossain G, Díaz M, Rocasalbas G, Tzanov T. Multifunctional modification of wool using an enzymatic process in aqueousorganic media. J. Biotechnology 2009, 141, 58-63.
• Hossain G, Daga J M , Riva A., Canal, J.M., Tzanov, T. Un proceso enzimático para lana resistente al encogimiento Química têxtil 2008, 199, 29-35.
• Hossain G, Riva A, Tzanov T. Simultaneous protease and transglutaminase treatment for shrink resistance of wool, Biocatalysis and Biotransformation 2008, 26(5), 405-411.
• Moldes D, Díaz M, Tzanov T, Vidal T. Comparative study of the efficiency of synthetic and natural mediators, Bioresource Technology 2008, 99, 7959-7965.
• Reyes-Alcatraz A, Tzanov T, Garriga P. Stabilization of Membrane Proteins: the case of G-protein coupled receptors, Engineering in Life Sciences 2008, 8 (3), 207-217.
• Basto C, Tzanov T, Cavaco-Paulo A. Combined ultrasound-laccase assisted bleaching of cotton. Ultrasonics Sonochemistry 2007, 14, 350-354.
• Calafell M, Diaz C, Hadzhiyska H, Gibert J M, Dagà J M, Tzanov T. Bio-catalyzed coloration of cellulose fibers, Biocatalysis and Biotransformation 2007, 25 , 336-340.
• Hadzhiyska H, Calafell M, Gibert J M, Dagà J M, Tzanov T. Laccase-assisted dyeing of cotton, Biotechnology Letters 2006, 28 , 755-759.
•  Calafell M, Klug-Santner B, Gubitz G, Garriga P. Dyeing behaviour of cotton fabric bioscoured with pectate lyase and polygalacturonase, Coloration Technology 2005, 121, 1-7.
• Pereira L, Bastos C, Tzanov T. Cavaco-Paulo A, Gübitz, G. Laccases from a newly isolated strain of Trametes hirsuta with potential in cotton bleaching. Environ. Chem. Lett. 2005, 3, 66-69.
• Shen J, Sampaio S, Bishop D., Miettinen - Oinonen A, Tzanov T. Progress on Enzymatic Preparation of Flax and Flax Wool Blends. AATCC Review 2005, 5 (5),  23-28.

Book chapters

• Zeinali R and Tzanov T. Injectable Smart Nanocomposite Hydrogels for Biomedical Applications, in "Injectable Smart Hydrogels for Biomedical Applications" edited by Mohan J, Ashammakhi N ant Rotimi E, ISBN: 978-1-83767-170-0, Royal Society of Chemistry, 2024, 215-243, https://doi.org/10.1039/BK9781837673070-00215
• Pérez-Rafael S, Ramon E, Tzanov T, Enzyme-Assisted Hydrogel Formation for Tissue Engineering Applications, in “Multifunctional Hydrogels for Biomedical Applications” edited by Pires R, Pashkuleva I, and Reis R, ISBN: 978-3-527-34716-2, Wiley-VCH GmbH, 2022.
• Morena A G, Ferreres G, Ivanova K, Pérez-Rafael S, Tzanov T, Antimicrobial Lightweight Materials and Components, in “Advanced Lightweight Multifunctional Materials” edited by Costa P, Costa C, and Lanceros-Mendez S, ISBN: 978-0-12-818501-8, Elsevier, 2020, 469-502.
• Stefanov I, Bassegoda A, Tzanov T, Biomedical textiles in “Advances in Textile Biotechnologies”, edited by Cavaco-Paulo A, Nierstrasz V, Wang Q, ISBN: 9780081026328, Woodhead Publishing, 2019.
• Ivanova A, Ivanova K, Tzanov T, Inhibition of Quorum-Sensing: A New Paradigm in Controlling Bacterial Virulence and Biofilm Formation, in "Biotechnological Applications of Quorum Sensing Inhibitors",  edited by Kalia, VC,  ISBN: 978-981-10-9026-43-21, Springer, Singapore, 2018, 3-21.
• Ivanova K, Bassegoda A, Tzanov T. Antibacterial Coatings on Medical Devices, in "Handbook of Antimicrobial Coatings", edited by Tiwari, A, ISBN: 978-0-12-811982-2, Elsevier Inc., USA, 2018, 487-509. doi: https://doi.org/10.1016/B978-0-12-811982-2.00021-4.
• Rivera D, Rommi K, Fernandes MM, Lantto R, Tzanov T. Enzyme-aided processing of rapeseed oil industry by-products into added value ingredients for food, cosmetic and pharmaceutical applications, in "Rapeseed: Chemical Composition, Production and Health Benefits", edited by White, M, ISBN: 33-47.978-1-63484-227-3, Nova science publishers Inc, Hauppauge, NY, 2016, 33-47.
• Ivanova K, Fernandes MM, Tzanov T. Strategies for silencing bacterial communication, in "Quorum Sensing vs Quorum Quenching: a Battle with no End in Sight", edited by Kalia, VC, Springer India, 2015.
• Francesko A, Fernandes MM, Rocasalbas G, Gautier S, Tzanov T. Polymers in wound repair, in "Advanced polymers in medicine", edited by Puoci F, ISBN: 978-3-319-12477-3, Springer International Publishing, 2014, 1-31.
• Ivanova K, Fernandes MM, Tzanov T. Current advances on bacterial pathogenesis inhibition and treatment strategies, in "Microbial Pathogens and Strategies for Combating Them: Science, Technology and Education", edited by Mendez-Vilas, A, Formatex Research Center, 2013.
• Francesko A, Fernandes MM, Tzanov T. Gallic acid implications in health: multi-therapeutic and protective agent, in “Handbook on Gallic Acid: Natural Occurrences, Antioxidant Properties and Health Implications” edited by Thompson, MA and Collins, PB, ISBN-13: 9781626189218, Nova Science Pub Inc, 2013.
• Díaz-González M, Francesko A, Fernandes MM, Tzanov T.  Myeloperoxidase – a paradoxical enzyme – from host defense to disease, in “Enzymes and Enzyme Activity: Structure, Biology and Clinical Significance” edited by  Lashinski, EM, Nova Science Publishers, ISBN: 978-1-62417-697-695, 2012.
• Touriño, S., Tzanov, T., Skirtenko, N., Angel, U., Gedanken A., Chitosan microspheres in "Handbook of chitosan research and applications", Edited by Richard G. Mackay and Jennifer M. Tait, ISBN: 978-1-61324-455-5, Nova science publishers Inc, Hauppauge, NY, 2012, 453-469.
• Francesko, A., Tzanov, T. Chitin, chitosan and derivatives for wound healing and tissue engineering in Advances in Biochemical Engineering/Biotechnology, Springer-Verlag, Berlin, Heidelberg, ISBN: 1616-8542, 2010, 1-27.
• Francesko, A., Díaz-González, M., Rocasalbas, G., Tzanov, T. Developments in the processing of chitin, chitosan and bacterial cellulose for textile and other applications in Advances in textile biotechnology, Woodhead Publishing Limited, ISBN: 978-1-84569- 625-2, 2010, 288-311.
• Tzanov, T., Cavaco-Paulo, Capitulo 10 "Surface modification of cellulose fibers with hydrolases and kinases", "Modified Fibers with Medical and Specialty Applications" ISBN 1-4020-3793-7, Editor: J. Vincent Edwards, Gisela Buschle-Diller and Steven C. Goheen,Springer, Dordrecht, The Netherlands, 2006, 159-180.

Patents

Molecular Biotechnology

Peer reviewed articles